27 February 2013
Vol 5, Issue 174
  • Editorial

    • No Time to Waste

      The United States must strengthen its support of the medical research and development ecosystem.

  • Focus

  • Research Articles

  • Editors' Choice

    • The Buzz in Chronic Wound Treatment

      Honey can be used as an antimicrobial to treat common bacteria in chronic skin wound infections.

    • Insights into Aging Vessels

      The transcription factor JunD links oxidative stress and vascular aging.

About The Cover

Cover image expansion

ONLINE COVER Lipoxin Doubles Up. Despite its many triggers—exercise, animals, cold air—the underlying causes of inflammation in asthma are still unknown. In this week’s issue, Barnig et al. found that type 2 innate lymphoid cells (ILC2s) promoted lung inflammation and natural killer (NK) cells induced eosinophil apoptosis in asthmatic patients. Addition of the drug lipoxin A4 (shown on the cover in a space-filling model) resolved the proinflammatory activities of both ILC2s and NK cells, giving new treatments for asthma a breath of fresh air. See related Focus by Peebles. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL MEDICINE]