Ovarian Aging: Breaking Up Is Hard to Fix

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  Ovarian Aging: Breaking Up Is Hard to Fix

  By Joshua Johnson, David L. Keefe

  Science Translational Medicine13 Feb 2013 : 172fs5

  Double-stranded breaks (DSBs) in DNA—which are essential for normal development—accumulate with age and contribute to reproductive aging. Age-related inhibition of DSB repair diminishes ovarian reserve in mice and women.

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  Ovarian Aging: Breaking Up Is Hard to Fix

  By Joshua Johnson, David L. Keefe

  Science Translational Medicine13 Feb 2013 : 172fs5

  Double-stranded breaks (DSBs) in DNA—which are essential for normal development—accumulate with age and contribute to reproductive aging. Age-related inhibition of DSB repair diminishes ovarian reserve in mice and women.

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