Research ArticleTraumatic Brain Injury

Mesenchymal Stem Cells Regulate Blood-Brain Barrier Integrity Through TIMP3 Release After Traumatic Brain Injury

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Science Translational Medicine  21 Nov 2012:
Vol. 4, Issue 161, pp. 161ra150
DOI: 10.1126/scitranslmed.3004660

Article Information

vol. 4 no. 161 161ra150

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 23, 2012
  • Accepted for publication October 28, 2012
  • .

Author Information

  1. Tyler Menge1,*,
  2. Yuhai Zhao2,*,
  3. Jing Zhao3,
  4. Kathryn Wataha1,
  5. Michael Gerber2,
  6. Jianhu Zhang4,
  7. Phillip Letourneau2,
  8. John Redell3,
  9. Li Shen4,
  10. Jing Wang4,
  11. Zhalong Peng2,
  12. Hasen Xue5,
  13. Rosemary Kozar2,
  14. Charles S. Cox Jr.5,
  15. Aarif Y. Khakoo6,
  16. John B. Holcomb2,
  17. Pramod K. Dash3 and
  18. Shibani Pati1,7,
  1. 1Blood Systems Research Institute, San Francisco, CA 94118, USA.
  2. 2Department of Surgery and Center for Translational Injury Research, The University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.
  3. 3Department of Neurobiology and Anatomy, The University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.
  4. 4Department of Biostatistics, M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  5. 5Department of Pediatric Surgery and Institute for Molecular Medicine, The University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.
  6. 6Amgen, South San Francisco, CA 94080, USA.
  7. 7University of California, San Francisco, San Francisco, CA 94118, USA.
  1. To whom correspondence should be addressed. E-mail: spati{at}bloodsystems.org
  • * These authors contributed equally to this work.

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