14 November 2012
Vol 4, Issue 160
  • Contents

    • Editorial

      • Regenerative Engineering

        The future of tissue regeneration lies in “regenerative engineering,” with biomaterials playing a key role.

    • Commentary

    • Perspectives

      • Building Vascular Networks

        Advances in generating vascular networks in biomaterials may aid translation of tissue engineering technologies.

    • State of the Art Review

    • Review

      • Engineering Complex Tissues

        Advances in tissue engineering technologies will enable regeneration of complex tissues and organs.

    • Editors' Choice

      • Calling All Satellite Cells!

        A signaling pathway crucial for satellite cell expansion may hold the key to enhancing cell-based therapies for muscle regeneration.

      • Reactivating the Natural Killer

        Natural killer cell dysfunction after surgical stress can be reversed with oncolytic viruses.

      • Analysis of Immunoparalysis

        An experimental model of human sepsis provides opportunities to test the in vivo effects of immunomodulatory interventions.

      • Weighty Considerations

        Weight loss–regulated marker is associated with glucose and fatty acid metabolism.

About The Cover

Cover image expansion

ONLINE COVER Biomaterials. This week, Science Translational Medicine teams up with Science to present a diverse set of articles that discusses the latest advances in biomaterials research. Because biomaterials play a major role in improving human health, the Science Translational Medicine articles focus on engineering complex tissues, designing biomaterials therapies for the clinic, efforts in vascularization, and regulatory considerations. Interactions between cells and their microenvironments (see cover) influence physiology, and biomaterials destined for the clinic seek to mimic this dynamic dance. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL MEDICINE]