Contents
Vol 4, Issue 160
Contents
Editorial
- Regenerative Engineering
The future of tissue regeneration lies in “regenerative engineering,” with biomaterials playing a key role.
Commentary
- What Is the Greatest Regulatory Challenge in the Translation of Biomaterials to the Clinic?
Leaders in the field comment on what they perceive to be the greatest barriers to biomaterial translation.
Perspectives
- Building Vascular Networks
Advances in generating vascular networks in biomaterials may aid translation of tissue engineering technologies.
- Dynamic Microenvironments: The Fourth Dimension
Four-dimensional cell matrices that recapitulate tissue and organ function will aid in the translation of cell-based therapies.
State of the Art Review
- Designing Regenerative Biomaterial Therapies for the Clinic
Several academic, regulatory, and clinical aspects should be considered when moving biomaterials from the lab to the patient.
Review
- Engineering Complex Tissues
Advances in tissue engineering technologies will enable regeneration of complex tissues and organs.
Editors' Choice
- Calling All Satellite Cells!
A signaling pathway crucial for satellite cell expansion may hold the key to enhancing cell-based therapies for muscle regeneration.
- Reactivating the Natural Killer
Natural killer cell dysfunction after surgical stress can be reversed with oncolytic viruses.
- Analysis of Immunoparalysis
An experimental model of human sepsis provides opportunities to test the in vivo effects of immunomodulatory interventions.
- Weighty Considerations
Weight loss–regulated marker is associated with glucose and fatty acid metabolism.