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Research ArticleCancer
Targeting Cancer with a Lupus Autoantibody
- James E. Hansen1,2,*,
- Grace Chan3,
- Yanfeng Liu1,
- Denise C. Hegan1,
- Shibani Dalal1,
- Eloise Dray4,†,
- Youngho Kwon4,
- Yuanyuan Xu4,
- Xiaohua Xu5,
- Elizabeth Peterson-Roth1,
- Erik Geiger1,
- Yilun Liu5,
- Joseph Gera3,6,
- Joann B. Sweasy1,2,7,8,
- Patrick Sung1,2,4,
- Sara Rockwell1,2,9,
- Robert N. Nishimura3,10,
- Richard H. Weisbart3 and
- Peter M. Glazer1,2,8,*
- 1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
- 2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
- 3Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA 91343, USA.
- 4Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, CT 06520, USA.
- 5Division of Radiation Biology, Beckman Research Institute, Duarte, CA 91010, USA.
- 6David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- 7Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
- 8Department of Genetics, Yale School of Medicine, New Haven, CT 06520, USA.
- 9Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
- 10Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
- ↵*To whom correspondence should be addressed. E-mail: james.e.hansen{at}yale.edu (J.E.H.); peter.glazer{at}yale.edu (P.M.G.)
-
↵† Present address: Australian Institute for Bioengineering and Nanotechnology (AIBN), University of Queensland, St Lucia 4072, Queensland, Australia.
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Science Translational Medicine 24 Oct 2012:
Vol. 4, Issue 157, pp. 157ra142
DOI: 10.1126/scitranslmed.3004385
Vol. 4, Issue 157, pp. 157ra142
DOI: 10.1126/scitranslmed.3004385
James E. Hansen
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
Grace Chan
3Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA 91343, USA.
Yanfeng Liu
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
Denise C. Hegan
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
Shibani Dalal
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
Eloise Dray
4Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, CT 06520, USA.
Youngho Kwon
4Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, CT 06520, USA.
Yuanyuan Xu
4Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, CT 06520, USA.
Xiaohua Xu
5Division of Radiation Biology, Beckman Research Institute, Duarte, CA 91010, USA.
Elizabeth Peterson-Roth
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
Erik Geiger
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
Yilun Liu
5Division of Radiation Biology, Beckman Research Institute, Duarte, CA 91010, USA.
Joseph Gera
3Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA 91343, USA.
6David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Joann B. Sweasy
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
7Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT 05405, USA.
8Department of Genetics, Yale School of Medicine, New Haven, CT 06520, USA.
Patrick Sung
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
4Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, CT 06520, USA.
Sara Rockwell
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
9Department of Pharmacology, Yale School of Medicine, New Haven, CT 06520, USA.
Robert N. Nishimura
3Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA 91343, USA.
10Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Richard H. Weisbart
3Veterans Affairs Greater Los Angeles Healthcare System, Sepulveda, CA 91343, USA.
Peter M. Glazer
1Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520, USA.
2Yale Cancer Center, Yale School of Medicine, New Haven, CT 06520, USA.
8Department of Genetics, Yale School of Medicine, New Haven, CT 06520, USA.
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