Contents
Vol 4, Issue 153
Contents
Perspective
- Pharmacogenomics and Patient Care: One Size Does Not Fit All
Pharmacogenomics research provides insights into a personalized approach to prescribing and dosing medications.
Research Articles
- Quantitative Analysis of the Human Airway Microbial Ecology Reveals a Pervasive Signature for Cystic Fibrosis
Deep sequencing of microbial marker genes in lung secretions revealed individualized microbiomes in healthy subjects that differed from stereotyped microbiomes of cystic fibrosis patients.
- An RNA Profile Identifies Two Subsets of Multiple Sclerosis Patients Differing in Disease Activity
A peripheral blood mononuclear cell transcriptional profile differentiates two subsets of multiple sclerosis patients differing in their probability of a relapse.
- Vascular Catheters with a Nonleaching Poly-Sulfobetaine Surface Modification Reduce Thrombus Formation and Microbial Attachment
Poly-sulfobetaine surface modification on a vascular catheter inhibits microbial adherence and thrombosis.
Review
- Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface
This Review discusses approaches to developing infection-reducing biomaterials that strike a balance between host tissue integration and prevention of microbial attachment.
Editors' Choice
- Regulation from the Inside Out
The PI3 kinase C2α in endothelial cells orchestrates the creation and maintenance of a healthy vascular system.
- The Stress of Combat
Combat stress has persistent and reversible adverse effects on the brain.
- Neutralizing Neutrophil Invasion
IL-17A antibodies decrease ischemic stroke injury in mice.
- The Lymph Node Labyrinth
Lymph node innate immune cells are structurally orientated to trap and eradicate entering pathogens.