Anthrax Vaccine–Induced Antibodies Provide Cross-Species Prediction of Survival to Aerosol Challenge | Science Translational Medicine

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Article Information

vol. 4 no. 151 151ra126

DOI:

https://doi.org/10.1126/scitranslmed.3004073

PubMed:

Published By:

American Association for the Advancement of Science

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History:

Received for publication March 28, 2012
Accepted for publication July 12, 2012
.

Copyright & Usage:

Copyright © 2012, American Association for the Advancement of Science

Author Information

Michael P. Fay¹,*,
Dean A. Follmann¹,
Freyja Lynn²,†,
Jarad M. Schiffer³,‡,
Gregory V. Stark⁴,
Robert Kohberger⁵,§,
Conrad P. Quinn³,‡ and
Edwin O. Nuzum²

¹Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, 6700B Rockledge Drive, Bethesda, MD 20892–7630, USA.
²Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, 6610 Rockledge Drive, Bethesda, MD 20892–6604, USA.
³Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA.
⁴Battelle, 505 King Avenue, Columbus, OH 43201, USA.
⁵Blair & Co., Greenwich, CT 06830, USA.

↵*To whom correspondence should be addressed. E-mail: mfay{at}niaid.nih.gov

↵† Present address: Center for Biologics Evaluation and Research, Office of Vaccines Research and Review, 9000 Rockville Pike, Bethesda, MD 20892, USA.
↵‡ The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.
↵§ Deceased. We dedicate this paper to him.

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Science Translational Medicine: 4 (151)

Science Translational Medicine

Vol 4, Issue 151
12 September 2012

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Anthrax Vaccine–Induced Antibodies Provide Cross-Species Prediction of Survival to Aerosol Challenge

By Michael P. Fay, Dean A. Follmann, Freyja Lynn, Jarad M. Schiffer, Gregory V. Stark, Robert Kohberger, Conrad P. Quinn, Edwin O. Nuzum

Science Translational Medicine12 Sep 2012 : 151ra126

Lethal toxin–neutralizing activity in serum after vaccination can provide cross-species predictions of survival against inhalation anthrax.

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Anthrax Vaccine–Induced Antibodies Provide Cross-Species Prediction of Survival to Aerosol Challenge

By Michael P. Fay, Dean A. Follmann, Freyja Lynn, Jarad M. Schiffer, Gregory V. Stark, Robert Kohberger, Conrad P. Quinn, Edwin O. Nuzum

Science Translational Medicine12 Sep 2012 : 151ra126

Lethal toxin–neutralizing activity in serum after vaccination can provide cross-species predictions of survival against inhalation anthrax.

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