Contents
Vol 4, Issue 151
Contents
Commentary
- Stem Cells, Dot-Com
Unregulated and medically unsupported stem cell–based treatments are being advertised online directly to consumers, requiring policy reform to protect patient safety.
Perspective
- Extrapolating from Animals to Humans
Clinical effectiveness for interventions in humans can only be speculated from animal studies.
Research Articles
- Sinus Microbiome Diversity Depletion and Corynebacterium tuberculostearicum Enrichment Mediates Rhinosinusitis
Enrichment of Corynebacterium tuberculostearicum caused by depletion of the sinus microbiome contributes to chronic rhinosinusitis.
- Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men
PrEP drug concentrations associated with ≥90% reduction in HIV acquisition in men who have sex with men are achieved with daily dosing.
- Anthrax Vaccine–Induced Antibodies Provide Cross-Species Prediction of Survival to Aerosol Challenge
Lethal toxin–neutralizing activity in serum after vaccination can provide cross-species predictions of survival against inhalation anthrax.
Editors' Choice
- A Model Challenge
There is still time to participate in an open computational challenge to identify predictors of breast cancer progression.
- Neutrophil Superheroes: Casting NETs to Catch Bacteria
Neutrophils can survive and continue crawling while they cast NETs to fight bacterial infection in vivo.
- Merging Electronics and Engineered Tissues
Three-dimensional tissue cultures embedded with flexible networks of transistors enable the spatially resolved sensing of cellular microenvironments.
- Depression: Just Say NO
Nitric oxide generation in the hippocampus may explain the “gender gap” in depression.
- You Can Have That Dessert—Sometimes
Caloric restriction does not increase longevity in rhesus monkeys.
- MOLDing Childhood Asthma
Exposure during infancy to molds common to water-damaged homes is associated with development of childhood asthma.