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Abstract
Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease.
Footnotes
Citation: J. R. Gerstner, I. J. Perron, A. I. Pack, The nexus of Aβ, aging, and sleep. Sci. Transl. Med. 4, 150fs34 (2012).
- Copyright © 2012, American Association for the Advancement of Science