FocusAlzheimer’s Disease

The Nexus of Aβ, Aging, and Sleep

See allHide authors and affiliations

Science Translational Medicine  05 Sep 2012:
Vol. 4, Issue 150, pp. 150fs34
DOI: 10.1126/scitranslmed.3004815

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease.


  • Citation: J. R. Gerstner, I. J. Perron, A. I. Pack, The nexus of Aβ, aging, and sleep. Sci. Transl. Med. 4, 150fs34 (2012).

View Full Text

Stay Connected to Science Translational Medicine