The Nexus of Aβ, Aging, and Sleep

Jason R. Gerstner; Isaac J. Perron; Allan I. Pack

doi:10.1126/scitranslmed.3004815

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Abstract

Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease.

Footnotes

Citation: J. R. Gerstner, I. J. Perron, A. I. Pack, The nexus of Aβ, aging, and sleep. Sci. Transl. Med. 4, 150fs34 (2012).

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Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid (Aβ) peptide, suggesting that sleep alterations could be an early event in Alzheimer’s disease (AD).

The Nexus of Aβ, Aging, and Sleep

Abstract

Footnotes

Science Translational Medicine

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