Research ArticleDyslipidemia

Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression

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Science Translational Medicine  22 Aug 2012:
Vol. 4, Issue 148, pp. 148ra115
DOI: 10.1126/scitranslmed.3003877

Article Information

vol. 4 no. 148 148ra115

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 14, 2012
  • Accepted for publication June 29, 2012
  • .

Author Information

  1. Brett Lauring1,*,
  2. Andrew K. P. Taggart1,*,
  3. James R. Tata1,
  4. Richard Dunbar2,
  5. Luzelena Caro1,
  6. Kang Cheng1,
  7. Jayne Chin1,
  8. Steven L. Colletti1,
  9. Josee Cote1,
  10. Sauzanne Khalilieh1,
  11. Jiajun Liu1,
  12. Wen-Lin Luo1,
  13. Alexandra A. MacLean1,
  14. Laurence B. Peterson1,
  15. Adam B. Polis1,
  16. Waheeda Sirah1,
  17. Tsuei-Ju Wu1,
  18. Xuan Liu1,
  19. Lan Jin1,
  20. Kenneth Wu1,
  21. P. Douglas Boatman3,
  22. Graeme Semple3,
  23. Dominic P. Behan3,
  24. Daniel T. Connolly3,
  25. Eseng Lai1,
  26. John A. Wagner1,
  27. Samuel D. Wright1,
  28. Cynthia Cuffie1,
  29. Yale B. Mitchel1,
  30. Daniel J. Rader2,
  31. John F. Paolini1,
  32. M. Gerard Waters1 and
  33. Andrew Plump1,
  1. 1Merck Sharp & Dohme Corp., Whitehouse Station, NJ 07065, USA.
  2. 2Institute for Translational Medicine and Therapeutics and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104–5158, USA.
  3. 3Arena Pharmaceuticals, San Diego, CA 92121, USA.
  1. To whom correspondence should be addressed. E-mail: Andrew.Plump{at}sanofi.com
  • * These authors contributed equally to this work.

  • Present address: Sanofi Research & Development, 55 Corporate Drive, Bridgewater, NJ 08807–5925, USA.

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