Research ArticleNipah Virus
A Hendra Virus G Glycoprotein Subunit Vaccine Protects African Green Monkeys from Nipah Virus Challenge
- Katharine N. Bossart1,2,*,
- Barry Rockx3,4,*,
- Friederike Feldmann5,
- Doug Brining6,
- Dana Scott6,
- Rachel LaCasse6,
- Joan B. Geisbert7,8,
- Yan-Ru Feng9,
- Yee-Peng Chan9,
- Andrew C. Hickey1,2,
- Christopher C. Broder9,†,
- Heinz Feldmann3,10 and
- Thomas W. Geisbert7,8
- 1Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.
- 2National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, MA 02118, USA.
- 3Laboratory of Virology, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
- 4Sealy Center for Vaccine Development, Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555–0610, USA.
- 5Offices of Operations and Management, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
- 6Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
- 7Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77550, USA.
- 8Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77550, USA.
- 9Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
- 10Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, MB R3T 2N2, Canada.
- ↵†To whom correspondence should be addressed. E-mail: christopher.broder{at}usuhs.edu
-
↵* These authors contributed equally to this work.
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Science Translational Medicine 08 Aug 2012:
Vol. 4, Issue 146, pp. 146ra107
DOI: 10.1126/scitranslmed.3004241
Vol. 4, Issue 146, pp. 146ra107
DOI: 10.1126/scitranslmed.3004241
Katharine N. Bossart
1Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.
2National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, MA 02118, USA.
Barry Rockx
3Laboratory of Virology, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
4Sealy Center for Vaccine Development, Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555–0610, USA.
Friederike Feldmann
5Offices of Operations and Management, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Doug Brining
6Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Dana Scott
6Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Rachel LaCasse
6Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Joan B. Geisbert
7Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77550, USA.
8Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77550, USA.
Yan-Ru Feng
9Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Yee-Peng Chan
9Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Andrew C. Hickey
1Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.
2National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, MA 02118, USA.
Christopher C. Broder
9Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Heinz Feldmann
3Laboratory of Virology, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
10Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, MB R3T 2N2, Canada.
Thomas W. Geisbert
7Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77550, USA.
8Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77550, USA.
