Contents
Vol 4, Issue 145
Contents
Focus
- β-Amyloid: Enemy or Remedy?
β-Amyloid can modulate the immune response in a mouse model of multiple sclerosis (Grant et al., this issue).
- Anti-CD25 Immunotherapy: Regulating the Regulators
Innate immunity, adaptive immunity, and antigen presentation collaborate to effect monoclonal antibody therapy in multiple sclerosis.
Research Articles
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
Anacardic acid attenuates mutant TDP-43–associated abnormalities in motor neurons derived from ALS patient–specific induced pluripotent stem cells.
- Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of β-Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis
β-Amyloid reduces inflammation and improves symptoms in a mouse model of multiple sclerosis.
- Inhibition of LTi Cell Development by CD25 Blockade Is Associated with Decreased Intrathecal Inflammation in Multiple Sclerosis
Daclizumab inhibition of inflammation in human autoimmunity is associated with blockade of lymphoid tissue inducer cell development.
Editors' Choice
- Unmasking Lung Injury in Sepsis
Degradation of the glycocalyx of lung endothelium promotes acute lung injury during sepsis.
- Prenatal Conditions Shape Cognition
Subtle differences in prenatal brain growth influence later brain maturation.
- Antiviral Traps: HIV Avoids a Sticky Situation
HIV is able to evade capture by neutrophil extracellular traps (NETs) by inducing dendritic cells to produce a NET-suppressive factor.
