Research ArticleCancer

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

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Science Translational Medicine  18 Jul 2012:
Vol. 4, Issue 143, pp. 143ra99
DOI: 10.1126/scitranslmed.3003807

Article Information

vol. 4 no. 143 143ra99

PubMed: 
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History: 
  • Received for publication February 2, 2012
  • Accepted for publication May 22, 2012

Author Information

  1. Laurie Menger1,2,3,
  2. Erika Vacchelli1,2,3,
  3. Sandy Adjemian1,2,3,
  4. Isabelle Martins1,2,3,
  5. Yuting Ma1,2,3,
  6. Shensi Shen1,2,3,
  7. Takahiro Yamazaki2,3,4,
  8. Abdul Qader Sukkurwala1,2,3,
  9. Mickaël Michaud1,2,3,
  10. Grégoire Mignot5,6,
  11. Frederic Schlemmer1,2,3,
  12. Eric Sulpice7,
  13. Clara Locher2,3,4,
  14. Xavier Gidrol7,
  15. François Ghiringhelli5,6,
  16. Nazanine Modjtahedi1,2,3,
  17. Lorenzo Galluzzi2,8,
  18. Fabrice André2,9,
  19. Laurence Zitvogel2,3,4,
  20. Oliver Kepp1,2,3,*, and
  21. Guido Kroemer1,8,10,11,12,*,
  1. 1INSERM, U848, F-94805 Villejuif, France.
  2. 2Institut Gustave Roussy, F-94805 Villejuif, France.
  3. 3Université Paris-Sud (Paris XI), F-94276 Le Kremlin-Bicêtre, France.
  4. 4INSERM, U1015, F-94805 Villejuif, France.
  5. 5Department of Medical Oncology, Georges-François Leclerc Center, F-21000 Dijon, France.
  6. 6INSERM Avenir Team, CRI-866, Université de Bourgogne, F-21000 Dijon, France.
  7. 7Laboratoire Biologie à Grande Echelle, Commissariat à l’Energie Atomique et aux Energies Alternatives, INSERM, U1038, Universite Joseph Fourier, F-38054 Grenoble, France.
  8. 8Université Paris Descartes (Paris V), Sorbonne Paris Cité, F-75270 Paris, France.
  9. 9INSERM, U981, F-94805 Villejuif, France.
  10. 10Metabolomics Platform, Institut Gustave Roussy, F-94805 Villejuif, France.
  11. 11Centre de Recherche des Cordeliers, F-75005 Paris, France.
  12. 12Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, F-75908 Paris, France.
  1. To whom correspondence should be addressed. E-mail: oliver.kepp{at}igr.fr (O.K.); kroemer{at}orange.fr (G.K.)
  • * These authors contributed equally to this work.

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