Research ArticleNeuroblastoma

Targeted Expression of Mutated ALK Induces Neuroblastoma in Transgenic Mice

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Science Translational Medicine  04 Jul 2012:
Vol. 4, Issue 141, pp. 141ra91
DOI: 10.1126/scitranslmed.3003967

Article Information

vol. 4 no. 141 141ra91

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 2, 2012
  • Accepted for publication May 7, 2012
  • .

Author Information

  1. Lukas C. Heukamp1,*,
  2. Theresa Thor2,*,
  3. Alexander Schramm2,
  4. Katleen De Preter3,
  5. Candy Kumps3,
  6. Bram De Wilde3,
  7. Andrea Odersky2,
  8. Martin Peifer4,5,
  9. Sven Lindner2,
  10. Annika Spruessel2,
  11. Filip Pattyn3,
  12. Pieter Mestdagh3,
  13. Björn Menten3,
  14. Steffi Kuhfittig-Kulle2,
  15. Annette Künkele2,
  16. Katharina König1,
  17. Lydia Meder1,
  18. Sampurna Chatterjee4,
  19. Roland T. Ullrich4,
  20. Stefanie Schulte2,
  21. Jo Vandesompele3,
  22. Frank Speleman3,
  23. Reinhard Büttner1,
  24. Angelika Eggert2 and
  25. Johannes H. Schulte2,
  1. 1Institute of Pathology, University Hospital Cologne, Kerpenerstrasse 62, 50924 Cologne, Germany.
  2. 2Department of Pediatric Oncology and Hematology, University Children’s Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
  3. 3Center for Medical Genetics Ghent, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.
  4. 4Max Planck Institute for Neurological Research with Klaus-Joachim-Zülch Laboratories of the Max Planck Society and the Medical Faculty of the University of Cologne, Gleueler Strasse 50, 50931 Köln, Germany.
  5. 5Institute of Translational Genomics, University of Cologne, Weyertal 155b, 50931 Cologne, Germany.
  1. To whom correspondence should be addressed. E-mail: johannes.schulte{at}uni-due.de
  • * These authors contributed equally to this work.

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