Research ArticleMuscular Dystrophy

Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy

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Science Translational Medicine  27 Jun 2012:
Vol. 4, Issue 140, pp. 140ra89
DOI: 10.1126/scitranslmed.3003541

Article Information

vol. 4 no. 140 140ra89

PubMed: 
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History: 
  • Received for publication December 1, 2011
  • Accepted for publication June 8, 2012
  • .

Author Information

  1. Francesco Saverio Tedesco1,2,3,*,
  2. Mattia F. M. Gerli1,2,
  3. Laura Perani2,,
  4. Sara Benedetti1,2,,
  5. Federica Ungaro4,,
  6. Marco Cassano5,,
  7. Stefania Antonini1,2,6,,
  8. Enrico Tagliafico7,8,
  9. Valentina Artusi7,8,
  10. Emanuela Longa9,10,
  11. Rossana Tonlorenzi2,
  12. Martina Ragazzi1,2,
  13. Giorgia Calderazzi2,6,
  14. Hidetoshi Hoshiya1,2,
  15. Ornella Cappellari1,2,
  16. Marina Mora11,
  17. Benedikt Schoser12,
  18. Peter Schneiderat12,
  19. Mitsuo Oshimura13,
  20. Roberto Bottinelli9,10,
  21. Maurilio Sampaolesi5,14,
  22. Yvan Torrente15,
  23. Vania Broccoli4 and
  24. Giulio Cossu1,2,6,*
  1. 1Department of Cell and Developmental Biology and Centre for Stem Cells and Regenerative Medicine, University College London, WC1E 6DE London, UK.
  2. 2Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.
  3. 3University College London Hospitals NHS Foundation Trust, UCH, NW1 2BU London, UK.
  4. 4Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
  5. 5Stem Cell Interdepartmental Institute, KU Leuven, 3000 Leuven, Belgium.
  6. 6Department of Biology, University of Milan, 20133 Milan, Italy.
  7. 7Department of Biomedical Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  8. 8Center for Genome Research, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  9. 9Department of Molecular Medicine and Interuniversity Institute of Myology, University of Pavia, 27100 Pavia, Italy.
  10. 10Fondazione Salvatore Maugeri (IRCCS), Scientific Institute of Pavia, 27100 Pavia, Italy.
  11. 11National Neurological Institute “C. Besta,” 20126 Milan, Italy.
  12. 12Department of Neurology, Ludwig-Maximilians-University, 81377 Munich, Germany.
  13. 13Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Tottori University, Yonago 683-8503, Japan.
  14. 14Human Anatomy, University of Pavia, 27100 Pavia, Italy.
  15. 15Department of Neurological Science, University of Milan, Fondazione IRCCS Policlinico Mangiagalli-Regina Elena, 20122 Milan, Italy.
  1. *To whom correspondence should be addressed. E-mail: f.s.tedesco{at}ucl.ac.uk (F.S.T.); g.cossu{at}ucl.ac.uk (G.C.)
  • These authors contributed equally to this work.

  • Present address: School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

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