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Research ArticleGene Therapy
Gene Therapy for Aromatic l-Amino Acid Decarboxylase Deficiency
- Wuh-Liang Hwu1,2,*,
- Shin-ichi Muramatsu3,
- Sheng-Hong Tseng4,
- Kai-Yuan Tzen5,6,
- Ni-Chung Lee1,
- Yin-Hsiu Chien1,
- Richard O. Snyder7,8,9,
- Barry J. Byrne7,
- Chun-Hwei Tai10 and
- Ruey-Meei Wu10
- 1Department of Pediatrics and Medical Genetics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan.
- 2Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei 100, Taiwan.
- 3Division of Neurology, Jichi Medical University, Shimotsuke, Tochigi 3290498, Japan.
- 4Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan.
- 5Department of Nuclear Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan.
- 6Molecular Imaging Center, National Taiwan University, Taipei 100, Taiwan.
- 7Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610–0266, USA.
- 8Center of Excellence for Regenerative Health Biotechnology, University of Florida College of Medicine, Gainesville, FL 32611–0585, USA.
- 9Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32610–0266, USA.
- 10Department of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100, Taiwan.
- ↵*To whom correspondence should be addressed. E-mail: hwuwlntu{at}ntu.edu.tw
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Science Translational Medicine 16 May 2012:
Vol. 4, Issue 134, pp. 134ra61
DOI: 10.1126/scitranslmed.3003640
Vol. 4, Issue 134, pp. 134ra61
DOI: 10.1126/scitranslmed.3003640
Wuh-Liang Hwu
Shin-ichi Muramatsu
Sheng-Hong Tseng
Kai-Yuan Tzen
Ni-Chung Lee
Yin-Hsiu Chien
Richard O. Snyder
Barry J. Byrne
Chun-Hwei Tai
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