02 May 2012
Vol 4, Issue 132
  • Contents

    • Focus

      • Complexities of the Uniquely Human Vagina

        The vaginal microbiome in healthy women changes over short periods of time, differs among individuals, and varies in its response to sexual intercourse.

    • Commentary

    • Research Articles

    • Editors' Choice

      • Calming RAGE in Alzheimer’s Disease

        A small molecule that blocks the RAGE receptor shows efficacy in a mouse model of Alzheimer’s disease.

      • Texting Can Be Healthy

        Text-message reminders can modestly increase influenza vaccine uptake among a low-income urban population.

      • Brain Tumor Diagnostics Go Micro

        MicroRNA levels in cerebrospinal fluid can be used as biomarkers to identify and track brain tumors.

      • Bypassing Alzheimer’s Disease

        After gastric bypass surgery, patients experience reduced inflammation and lower blood levels of proteins related to Alzheimer’s disease.

About The Cover

Cover image expansion

ONLINE COVER Ladies First. The human female form has long been a source of inspiration for artists. Scientists, too, explore the female form—and function. In this week’s issue of Science Translational Medicine, Gajer and colleagues use sophisticated techniques and mathematical models to assess changes over time in the bacterial populations present in the vaginas of healthy, reproductively competent women. The new work reveals that the human vaginal microbiome is much more complex and diverse than previously imagined. See also the accompanying Focus by Witkin and Ledger, who discuss implications of the new research in health and disease. [Matisse, Blue Nude (after French artist Henri Matisse, 1869 to 1954)] [CREDIT: SHUTTERSTOCK/IMAGEZEBRA]