25 April 2012
Vol 4, Issue 131

About The Cover

Cover image expansion

ONLINE COVER Approximating Autism. Although mice are not people, some strains of mice have characteristic behaviors that are very much like the ones physicians use to diagnose autism spectrum disorder, as depicted by the solitary mouse in the front.of the illustration. Like people with autism, this mouse does not interact much with its species-mates. Silverman et al. treat mice that have autistic-like behaviors with a glutamate receptor antagonist and show that the mice become more sociable. The drug is safe for humans and may be a possible treatment for individuals with autism spectrum disorder. [CREDIT: Y. HAMMOND/SCIENCE TRANSLATIONAL MEDICINE]