Pluripotent Stem Cell–Based Cancer Therapy: Promise and Challenges

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Science Translational Medicine  28 Mar 2012:
Vol. 4, Issue 127, pp. 127ps9
DOI: 10.1126/scitranslmed.3003920


The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.

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