Contents
Vol 4, Issue 126
Contents
Perspective
- Merging Systems Biology with Pharmacodynamics
Enhanced pharmacodynamic models combine favorable features of systems biology and traditional models and may form the basis of precision medicine.
Research Articles
- Characterization of Circulating Endothelial Cells in Acute Myocardial Infarction
Features of endothelial cells in blood samples may eventually permit prediction of atherosclerotic plaque rupture events.
- Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
Prostaglandin D2 inhibits hair growth through its receptor, GPR44, and this pathway could serve as a new target for developing treatments for male pattern baldness.
- Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics
Methicillin-resistant Staphylococcus aureus infection can be treated effectively by combining a β-lactam antibiotic with a drug that targets FtsZ.
Editors' Choice
- Twin Peaks
Genetic factors regulate the brain’s high-frequency gamma waves, which are disrupted in schizophrenia.
- The Gall of Some Bacteria: Strange Behavior by Salmonella
Salmonella shows reduced virulence gene expression when growing on bile in the gallbladder.
- A Painful Question of Metabolism
Metabolomics analysis implicates altered sphingolipids in chronic neuropathic pain.
- If I Had a Nickel for Every Wheeze
Rhinovirus infection may exacerbate asthma symptoms by inducing type III interferon lambda.