Research ArticleCancer Vaccines

Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses

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Science Translational Medicine  08 Feb 2012:
Vol. 4, Issue 120, pp. 120ra16
DOI: 10.1126/scitranslmed.3002868

Article Information

vol. 4 no. 120 120ra16

DOI: 
https://doi.org/10.1126/scitranslmed.3002868
PubMed: 
22323829
Published By: 
American Association for the Advancement of Science
Print ISSN: 
1946-6234
Online ISSN: 
1946-6242
History: 
  • Received for publication July 6, 2011
  • Accepted for publication December 29, 2011
  • .
Copyright & Usage: 
Copyright © 2012, American Association for the Advancement of Science

Author Information

  1. Johan Garaude1,2,
  2. Andrew Kent1,
  3. Nico van Rooijen3 and
  4. J. Magarian Blander1,*
  1. 1Immunology Institute, Department of Medicine, and The Tisch Cancer Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA.
  2. 2INSERM U1040, Institute for Research in Biotherapy, 80 Avenue Augustin Fliche, 34295 Montpellier Cedex 5, France.
  3. 3Department of Molecular Cell Biology, Faculty of Medicine, Vrije Universiteit University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, Netherlands.
  1. ↵*To whom correspondence should be addressed. E-mail: julie.blander{at}mssm.edu

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  • Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses

    By Johan Garaude, Andrew Kent, Nico van Rooijen, J. Magarian Blander

    Science Translational Medicine : 120ra16

    A cancer vaccine of irradiated tumor cells expressing flagellin primes effective NLRC4/NAIP5- and TLR5-dependent antitumor immune responses.

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