Contents
Vol 4, Issue 116
Contents
Perspective
- Magnetic Resonance Metabolic Imaging of Glioma
Noninvasive spectroscopic imaging of mutated enzymes and their metabolites could represent a new paradigm in glial tumor management.
Research Articles
- Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy
2-Hydroxyglutarate, a metabolite overproduced in IDH-mutated gliomas, can be detected noninvasively in patients with brain tumors by optimized magnetic resonance spectroscopy.
- Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas
2-Hydroxyglutarate can be detected ex vivo in biopsy tissue from IDH1-mutant low-grade gliomas with proton high-resolution magic angle spinning NMR spectroscopy.
- Alcohol Consumption Induces Endogenous Opioid Release in the Human Orbitofrontal Cortex and Nucleus Accumbens
Endogenous opioids are released in reward-related brain areas after an alcoholic drink to a greater extent in heavy drinkers than in control subjects.
Editors' Choice
- Building a Preventive Medicine Model with Genetic Scoring
A new genetic risk score promises personalized risk prediction for cardiovascular disease in diabetics.
- A New FIX for Hemophilia B
An improved gene therapy strategy results in an encouraging reduction in factor IX infusions for hemophilia B patients.
- The Holy Grail of Hepatitis C Treatment
A model predicts sustained virological response to hepatitis C treatment.
- Measles Versus Melanoma
A measles vaccine virus modulates the innate immune system and promotes virus-mediated death of malignant melanoma cells.