Research ArticleDrug Development

A Computational Model to Predict the Effects of Class I Anti-Arrhythmic Drugs on Ventricular Rhythms

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Science Translational Medicine  31 Aug 2011:
Vol. 3, Issue 98, pp. 98ra83
DOI: 10.1126/scitranslmed.3002588

Article Information

vol. 3 no. 98 98ra83

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 29, 2011
  • Accepted for publication June 23, 2011

Author Information

  1. Jonathan D. Moreno1,2,
  2. Z. Iris Zhu2,
  3. Pei-Chi Yang3,
  4. John R. Bankston4,
  5. Mao-Tsuen Jeng3,
  6. Chaoyi Kang3,
  7. Lianguo Wang3,
  8. Jason D. Bayer5,
  9. David J. Christini2,
  10. Natalia A. Trayanova5,
  11. Crystal M. Ripplinger3,
  12. Robert S. Kass4 and
  13. Colleen E. Clancy3,*
  1. 1Tri-Institutional MD-PhD Program, Weill Cornell Medical College/The Rockefeller University/Sloan-Kettering Cancer Institute, New York, NY 10021, USA.
  2. 2Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.
  3. 3Department of Pharmacology, University of California, Davis, CA 95616–8636, USA.
  4. 4Department of Pharmacology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA.
  5. 5Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, 3400 North Charles Street, CSEB, Room 216, Baltimore, MD 21218, USA.
  1. *To whom correspondence should be addressed. E-mail: ceclancy{at}ucdavis.edu

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