Research ArticleImmunodeficiency

Long-Term Persistence of a Polyclonal T Cell Repertoire After Gene Therapy for X-Linked Severe Combined Immunodeficiency

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Science Translational Medicine  24 Aug 2011:
Vol. 3, Issue 97, pp. 97ra79
DOI: 10.1126/scitranslmed.3002715

Article Information

vol. 3 no. 97 97ra79

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 27, 2011
  • Accepted for publication July 1, 2011
  • .

Author Information

  1. H. Bobby Gaspar1,2,
  2. Samantha Cooray1,2,
  3. Kimberly C. Gilmour1,2,
  4. Kathryn L. Parsley1,2,
  5. Stuart Adams3,
  6. Steven J. Howe1,
  7. Abdulaziz Al Ghonaium4,
  8. Jinhua Bayford1,2,
  9. Lucinda Brown1,2,
  10. E. Graham Davies1,2,
  11. Christine Kinnon1 and
  12. Adrian J. Thrasher1,2,*
  1. 1Centre for Immunodeficiency, Molecular Immunology Unit, Institute of Child Health, University College London, London WC1N 1EH, UK.
  2. 2Department of Clinical Immunology, Great Ormond Street Hospital NHS Trust, London WC1N 3JH, UK.
  3. 3Department of Bone Marrow Transplantation, Great Ormond Street Hospital NHS Trust, London WC1N 3JH, UK.
  4. 4Department of Paediatric Allergy/Immunology, King Faisal Specialist Hospital and Research Centre, Riyadh 1121, Saudi Arabia.
  1. *To whom correspondence should be addressed. E-mail: a.thrasher{at}ich.ucl.ac.uk

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