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Research ArticleMuscular Dystrophy
Stem Cell–Mediated Transfer of a Human Artificial Chromosome Ameliorates Muscular Dystrophy
- Francesco Saverio Tedesco1,2,
- Hidetoshi Hoshiya1,
- Giuseppe D’Antona3,
- Mattia F. M. Gerli1,
- Graziella Messina1,4,
- Stefania Antonini1,
- Rossana Tonlorenzi1,
- Sara Benedetti1,5,
- Libera Berghella6,
- Yvan Torrente7,
- Yasuhiro Kazuki8,
- Roberto Bottinelli3,9,
- Mitsuo Oshimura8 and
- Giulio Cossu1,4,*
- 1Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.
- 2Vita-Salute San Raffaele University, 20132 Milan, Italy.
- 3Department of Physiology and Interuniversity Institute of Myology, University of Pavia, 27100 Pavia, Italy.
- 4Department of Biology, University of Milan, 20133 Milan, Italy.
- 5Department of Histology and Medical Embryology, “Sapienza” University of Rome, 00161 Rome, Italy.
- 6Casa di Cura San Raffaele, 67039 Sulmona, L’Aquila, Italy.
- 7Department of Neurological Science, University of Milan, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico Mangiagalli-Regina Elena, 20122 Milan, Italy.
- 8Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Tottori University, Yonago 683-8503, Japan.
- 9Fondazione Salvatore Maugeri (IRCCS), Scientific Institute of Pavia, 27100 Pavia, Italy.
- ↵*To whom correspondence should be addressed. E-mail: cossu.giulio{at}hsr.it
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Science Translational Medicine 17 Aug 2011:
Vol. 3, Issue 96, pp. 96ra78
DOI: 10.1126/scitranslmed.3002342
Vol. 3, Issue 96, pp. 96ra78
DOI: 10.1126/scitranslmed.3002342
Francesco Saverio Tedesco
Hidetoshi Hoshiya
Giuseppe D’Antona
Mattia F. M. Gerli
Graziella Messina
Stefania Antonini
Rossana Tonlorenzi
Sara Benedetti
Libera Berghella
Yvan Torrente
Yasuhiro Kazuki
Roberto Bottinelli
Mitsuo Oshimura
Giulio Cossu
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