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- Is a single type of data sufficient for accurate computational drug repositioning?Show More
Sir,
We read with interest the article by Dudley et al, "Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease". The authors used a single type of data, namely public microarray data, to create gene expression signatures for drugs and diseases, and compared these signatures to arrive at novel repositioning candidates for Inflammatory Bowel Disease (IBD). They found topiramat...
Competing Interests: None declared.