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Curaxins: Anticancer Compounds That Simultaneously Suppress NF-κB and Activate p53 by Targeting FACT

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Science Translational Medicine  10 Aug 2011:
Vol. 3, Issue 95, pp. 95ra74
DOI: 10.1126/scitranslmed.3002530

Article Information

vol. 3 no. 95 95ra74

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 15, 2011
  • Accepted for publication July 22, 2011
  • .

Author Information

  1. Alexander V. Gasparian1,*,
  2. Catherine A. Burkhart1,*,
  3. Andrei A. Purmal1,
  4. Leonid Brodsky1,
  5. Mahadeb Pal2,,
  6. Madhi Saranadasa2,,
  7. Dmitry A. Bosykh1,
  8. Mairead Commane2,
  9. Olga A. Guryanova3,
  10. Srabani Pal2,
  11. Alfiya Safina2,
  12. Sergey Sviridov4,
  13. Igor E. Koman2,
  14. Jean Veith2,
  15. Anton A. Komar5,
  16. Andrei V. Gudkov1,2 and
  17. Katerina V. Gurova1,2,§
  1. 1Cleveland BioLabs Inc., Buffalo, NY 14203, USA.
  2. 2Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.
  3. 3Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  4. 4ChemBridge Corp., San Diego, CA 92121, USA.
  5. 5Center for Gene Regulation in Health and Disease, Department of Biology, Cleveland State University, Cleveland, OH 44105, USA.
  1. §To whom correspondence should be addressed. E-mail: katerina.gurova{at}roswellpark.org

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