Research ArticleHepatitis C Virus

A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques

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Science Translational Medicine  03 Aug 2011:
Vol. 3, Issue 94, pp. 94ra71
DOI: 10.1126/scitranslmed.3002330

Article Information

vol. 3 no. 94 94ra71

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 25, 2011
  • Accepted for publication June 2, 2011
  • .

Author Information

  1. Pierre Garrone1,*,
  2. Anne-Catherine Fluckiger1,,
  3. Philippe E. Mangeot1,
  4. Emmanuel Gauthier2,
  5. Pia Dupeyrot-Lacas1,
  6. Jimmy Mancip1,
  7. Arnaud Cangialosi1,
  8. Isaure Du Chéné1,
  9. Roger LeGrand3,
  10. Isabelle Mangeot3,
  11. Dimitri Lavillette2,
  12. Bertrand Bellier4,5,6,
  13. François-Loic Cosset2,,
  14. Frederic Tangy7,,
  15. David Klatzmann4,5,6,8,§ and
  16. Charlotte Dalba1,9,§
  1. 1Epixis S.A., F-69007 Lyon, France.
  2. 2Université de Lyon, Université Claude Bernard Lyon I, IFR128; INSERM U758; ENS de Lyon, F-69007 Lyon, France.
  3. 3CEA, Service de Neurovirologie (DSV/DRM), CRSSA, Institut Paris-Sud sur les Cytokines, F-92260 Fontenay aux Roses, France.
  4. 4Université Pierre et Marie Curie Paris 06, UMR7211, Immunology-Immunopathology-Immunotherapy (I3), F-75013 Paris, France.
  5. 5CNRS, UMR7211, I3, F-75013 Paris, France.
  6. 6INSERM, UMR_S959, I3, F-75013 Paris, France.
  7. 7Unité de Génomique Virale et Vaccination, Department of Virology, Institut Pasteur, CNRS URA 3015, F-75015 Paris, France.
  8. 8AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy, F-75013 Paris, France.
  9. 9Epixis S.A., F-75013 Paris, France.
  1. §To whom correspondence should be addressed. E-mail: david.klatzmann{at}upmc.fr (D.K.); cd{at}epixis.com (C.D.)

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