Contents
Vol 3, Issue 94
Contents
Commentary
- Defining Success for Translational Research Organizations
To promote translational research foundations require a flexible framework for performance assessment.
Perspective
- Progress Toward Development of a Hepatitis C Vaccine with Broad Shoulders
A rational, mechanism-based design of vaccine immunogens may be capable of eliciting potent, broadly neutralizing antibodies against HCV.
Research Articles
- Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality
A screen identifies a drug that specifically kills glycolysis-dependent cancer cells by inhibiting glucose uptake.
- A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques
Virus-like particles pseudotyped with heterologous viral envelopes stimulate broadly cross-neutralizing antibodies against HCV.
- Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA
Urine TMPRSS2:ERG gene fusion could be used for stratification of patients at higher risk for prostate cancer.
Editors' Choice
- Minimizing the Mischief of Mineralocorticoids
Reversing the adverse effects of mineralocorticoids in mice may have important implications for human heart health
- Cancer Returns
Genetic variants on chromosome 6 are associated with risk for second cancers after radiation therapy for childhood Hodgkin’s lymphoma.
- Can Anesthesia Make You Spineless?
The intravenous anesthetic propofol alters dendritic spines and synaptic organization in the neonatal cortex, raising questions about its toxicity.
- The "Eyes" Have It
An autoimmune response to the retina is involved in the pathogenesis of human uveitis.
- Understanding the Regulatory Pathway One Video at a Time
Online instruction guides scientists through the regulatory process for complex regenerative medicine products.
Podcast
- Science Translational Medicine Podcast: 3 August 2011
A conversation with David Klatzmann about a new vaccine platform to induce broadly neutralizing antibodies to hepatitis C virus.
Erratum
