Research ArticleCancer

Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development

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Science Translational Medicine  20 Jul 2011:
Vol. 3, Issue 92, pp. 92ra66
DOI: 10.1126/scitranslmed.3002543

Article Information

vol. 3 no. 92 92ra66

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 19, 2011
  • Accepted for publication June 28, 2011
  • .

Author Information

  1. Jian Wu1,*,
  2. Hanno Matthaei2,*,
  3. Anirban Maitra2,
  4. Marco Dal Molin2,
  5. Laura D. Wood2,
  6. James R. Eshleman2,
  7. Michael Goggins2,
  8. Marcia I. Canto3,
  9. Richard D. Schulick3,
  10. Barish H. Edil3,
  11. Christopher L. Wolfgang3,
  12. Alison P. Klein2,
  13. Luis A. Diaz Jr.1,
  14. Peter J. Allen4,
  15. C. Max Schmidt5,
  16. Kenneth W. Kinzler1,
  17. Nickolas Papadopoulos1,
  18. Ralph H. Hruban2 and
  19. Bert Vogelstein1,
  1. 1Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA.
  2. 2Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.
  3. 3Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.
  4. 4Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  5. 5Departments of Surgery, Biochemistry and Molecular Biology, Indiana University, Indianapolis, IN 46202, USA.
  1. To whom correspondence should be addressed. E-mail: bertvog{at}gmail.com

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