Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

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  Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

  By Maria Scarselli, Beatrice Aricò, Brunella Brunelli, Silvana Savino, Federica Di Marcello, Emmanuelle Palumbo, Daniele Veggi, Laura Ciucchi, Elena Cartocci, Matthew James Bottomley, Enrico Malito, Paola Lo Surdo, Maurizio Comanducci, Marzia Monica Giuliani, Francesca Cantini, Sara Dragonetti, Annalisa Colaprico, Francesco Doro, Patrizia Giannetti, Michele Pallaoro, Barbara Brogioni, Marta Tontini, Markus Hilleringmann, Vincenzo Nardi-Dei, Lucia Banci, Mariagrazia Pizza, Rino Rappuoli

  Science Translational Medicine13 Jul 2011 : 91ra62

  A single chimeric protein induces protective immunity against all meningococcal B strains with implications for producing broadly protective vaccines.

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  Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

  By Maria Scarselli, Beatrice Aricò, Brunella Brunelli, Silvana Savino, Federica Di Marcello, Emmanuelle Palumbo, Daniele Veggi, Laura Ciucchi, Elena Cartocci, Matthew James Bottomley, Enrico Malito, Paola Lo Surdo, Maurizio Comanducci, Marzia Monica Giuliani, Francesca Cantini, Sara Dragonetti, Annalisa Colaprico, Francesco Doro, Patrizia Giannetti, Michele Pallaoro, Barbara Brogioni, Marta Tontini, Markus Hilleringmann, Vincenzo Nardi-Dei, Lucia Banci, Mariagrazia Pizza, Rino Rappuoli

  Science Translational Medicine13 Jul 2011 : 91ra62

  A single chimeric protein induces protective immunity against all meningococcal B strains with implications for producing broadly protective vaccines.

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