PerspectiveSepsis

Broken Barriers: A New Take on Sepsis Pathogenesis

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Science Translational Medicine  22 Jun 2011:
Vol. 3, Issue 88, pp. 88ps25
DOI: 10.1126/scitranslmed.3002011

Article Information

vol. 3 no. 88 88ps25

DOI: 
https://doi.org/10.1126/scitranslmed.3002011
PubMed: 
21697528
Published By: 
American Association for the Advancement of Science
Print ISSN: 
1946-6234
Online ISSN: 
1946-6242
History: 
  • .
Copyright & Usage: 
Copyright © 2011, American Association for the Advancement of Science

Author Information

  1. Neil M. Goldenberg1,*,
  2. Benjamin E. Steinberg1,*,
  3. Arthur S. Slutsky2,3,4 and
  4. Warren L. Lee2,4,†
  1. 1Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
  2. 2Keenan Research Center of the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario M5B 1W8, Canada.
  3. 3Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.
  4. 4Divisions of Respirology and Critical Care Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
  5. *These authors contributed equally to this work.
  1. ↵†Corresponding author. E-mail: warren.lee{at}utoronto.ca

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  • Broken Barriers: A New Take on Sepsis Pathogenesis

    By Neil M. Goldenberg, Benjamin E. Steinberg, Arthur S. Slutsky, Warren L. Lee

    Science Translational Medicine : 88ps25

    Recent data indicate that disruption of the microvascular endothelial barrier is a key determinant of the pathogenesis of sepsis.

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