08 June 2011
Vol 3, Issue 86

About The Cover

Cover image expansion

ONLINE COVER Playing Ping Pong with Proteins. To understand how genes implicated in autism may be interconnected, Sakai et al. have built a protein-protein interaction network of autism-associated genes (pictured). This network joins the dots connecting autism-associated genes with each other (blue lines), with known binding partners (orange dots), and with new binding partners (purple dots). The plethora of new connections (green lines) unearths unexpected molecular pathways that may converge in the pathogenesis of autism.  [CREDIT: Y. SAKAI AND H. Y. ZOGHBI]