PodcastAlzheimer’s Disease

Science Translational Medicine Podcast: 25 May 2011

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Science Translational Medicine  25 May 2011:
Vol. 3, Issue 84, pp. 84pc7
DOI: 10.1126/scitranslmed.3002671

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  • Science Translational Medicine Podcast: 25 May 2011

    Participants: Steven M. Paul and Orla Smith

    A conversation with Steven M. Paul about a designer therapeutic antibody with potential for treating Alzheimer's disease.

    Highlighted articles:

    S. M. Paul, Therapeutic Antibodies for Brain Disorders. Sci. Transl. Med. 3, 84ps20 (2011).

    J. K. Atwal, Y. Chen, C. Chiu, D. L. Mortensen, W. J. Meilandt, Y. Liu, C. E. Heise, K. Hoyte, W. Luk, Y. Lu, K. Peng, P. Wu, L. Rouge, Y. Zhang, R. A. Lazarus, K. Scearce-Levie, W. Wang, Y. Wu, M. Tessier-Lavigne, R. J. Watts, A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo. Sci. Transl. Med. 3, 84ra43 (2011).

    Y. J. Yu, Y. Zhang, M. Kenrick, K. Hoyte, W. Luk, Y. Lu, J. Atwal, J. M. Elliott, S. Prabhu, R. J. Watts, M. S. Dennis, Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target. Sci. Transl. Med. 3, 84ra44 (2011).

    Length: 9.07 minutes

    File size: 8.35 MB

    Listen to Podcast | Download the Transcript

    Featured Perspective Article | Featured Research Article 1 | Featured Research Article 2

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