Contents
Vol 3, Issue 70
Contents
Commentary
- Thinking Outside the Box: Fostering Innovation and Non–Hypothesis-Driven Research at NIH
NIH's programs to fund the development of high-risk technologies play an important role in translational research.
Perspective
- For Placebo Effects in Medicine, Seeing Is Believing
Noninvasive whole-brain imaging can enhance our understanding of brain-based placebo effects.
Research Articles
- Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans
Ecuadorians who have a genetic mutation in the growth hormone receptor almost never die of cancer or diabetes complications, possibly because of high resistance to oxidative damage and low circulating insulin.
- The Effect of Treatment Expectation on Drug Efficacy: Imaging the Analgesic Benefit of the Opioid Remifentanil
An individual’s expectation that a pain treatment will or will not work can alter both its subjective effectiveness and the pain-related activity in the brain.
Editors' Choice
- Stem Cell Therapy Works (in Mice Models of Emphysema)!
Autologous adipose-derived stem cells attenuate both pulmonary and extrapulmonary effects of cigarette smoke exposure.
- Growth Factor Makes Memories Stick
Insulin-like growth factor II forestalls forgetting by boosting long-term potentiation and memory retention.
- Shining a Light on Stroke
In vivo mouse model yields unique insights into brain responses to stroke.
Letter
- Comment on “Multidimensional Results Reporting to Participants in Genomic Studies: Getting It Right”
The Commentary by Kohane and Taylor published on 23 June 2010, mistakenly indicates that the NHLBI Working Group advocated that researchers keep genetic information from research subjects if an intervention is not available for the disease.
