09 February 2011
Vol 3, Issue 69

About The Cover

Cover image expansion

ONLINE COVER A Tangled Web. A cast of mouse retinal blood vessels imaged by environmental scanning electron microscopy and colorized. This abnormally anarchic vascular bed is representative of the pathological vasculature found in diabetic retinopathy and retinopathy of prematurity. Sapieha et al. report that ω-3 polyunsaturated fatty acids reduce this abnormal vasculature in part through a metabolite of the enzyme 5-lipoxygenase. [CREDIT: P. SAPIEHA, J. SAPIEHA, and M. NELEA]