Contents
Vol 3, Issue 68
Contents
Perspective
- Humanizing Animal Models: A Key to Autoimmune Diabetes Treatment
A new humanized mouse model can be used to predict the clinical behavior of therapeutic antibodies for the treatment of Type 1 diabetes.
Research Articles
- Readily Available Tissue-Engineered Vascular Grafts
Nonimmunogenic, tissue-engineered vascular grafts stored long-term maintain their patency, strength, and function after transplant in large-animal models.
- Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance
Human CD3 transgenic mice offer a unique preclinical tool to test drugs promoting immune tolerance.
Editors' Choice
- Estrogen and Energy Balance
Nonclassical estrogen signaling mediates estrogen’s effect on metabolism.
- Adiponectin Battles Ceramides
The beneficial effects of adiponectin are mediated through the ceramidase activity of its receptor.
- Going With the Flow
Prolonged growth factor delivery using a hydrogel improves blood vessel formation in the heart.
Podcast
- Science Translational Medicine Podcast: 2 February 2011
A conversation with Shannon Dahl about how to bioengineer off-the-shelf vascular grafts for use in surgical transplantation.