Contents
Vol 3, Issue 67
Contents
Commentary
- Between Confidentiality and Scientific Exchange: The Place of Publication in Drug Discovery and Pharmaceutical Research
A combined preclinical and clinical publication might be the ideal approach in translational medicine.
Research Articles
- Uroporphyrinogen Decarboxylase Is a Radiosensitizing Target for Head and Neck Cancer
Uroporphyrinogen decarboxylase inhibition sensitizes head and neck cancer to both radiotherapy and chemotherapy.
- Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease
Bioenergetic properties differentiate alloreactive T cells from other proliferating cells and can be exploited to arrest GVHD in mice.
Editors' Choice
- An Epigenetic Road to Genome Instability
The histone methyltransferase EZH2 promotes genomic instability and oncogenic signaling in putative breast cancer stem cells.
- Yet Another Reason Rats Don’t Take Day Jobs
Feeding rats during the day rather than during their normal night pattern promotes obesity.
- Bacterial Breakaway
Peptides produced by Staphylococcus epidermidis promote dissemination of this bacterium from biofilms, leading to systemic infection in catheterized patients.