Contents
Vol 3, Issue 114
Contents
Perspective
- Mapping the Road Forward in Alzheimer’s Disease
A better understanding of genetics, protein aggregation, and neurobiology combined with improved clinical trial design is needed to combat Alzheimer’s disease.
Research Articles
- Predicting Adverse Drug Events Using Pharmacological Network Models
A network-based method that uses available pharmacosafety data can predict yet-to-be-discovered adverse drug events to help reduce drug-associated morbidity and mortality.
- Dynamics of Dengue Disease Severity Determined by the Interplay Between Viral Genetics and Serotype-Specific Immunity
The complex interactions between serotype-specific immunity and viral genetics drive dengue disease outcomes in endemic populations.
Review
- Forty-Year Journey of Angiogenesis Translational Research
Antiangiogenic drugs successfully treat retinal vascular diseases, but challenges remain in the realm of cancer therapy.
Editors' Choice
- Far from Home
Circulating bone cell precursors might promote ossification in diseased aortic valves.
- Dissecting “Normal” in Leukemia
Abnormal single-nucleotide polymorphisms are linked to worse outcomes in acute myelogenous leukemia patients with normal karyotypes.
- Acetylcholine: Working on Working Memory
Depletion of cholinergic neurons in the prefrontal cortex causes loss of a specific memory function in rhesus monkeys.
- Prodrug Progress
Microspheres encapsulating a prodrug of L-dopa maintain levels of dopamine in the brain better than L-dopa.
Erratum
