Research ArticleMetabolic Disease

Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1

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Science Translational Medicine  14 Dec 2011:
Vol. 3, Issue 113, pp. 113ra126
DOI: 10.1126/scitranslmed.3002669

Article Information

vol. 3 no. 113 113ra126

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 17, 2011
  • Accepted for publication November 3, 2011
  • .

Author Information

  1. Ai-Luen Wu1,*,
  2. Ganesh Kolumam2,*,
  3. Scott Stawicki3,
  4. Yongmei Chen3,
  5. Jun Li4,
  6. Jose Zavala-Solorio2,
  7. Khanhky Phamluong1,
  8. Bo Feng1,
  9. Li Li5,
  10. Scot Marsters4,
  11. Lance Kates2,
  12. Nicholas van Bruggen2,
  13. Maya Leabman6,
  14. Anne Wong7,
  15. David West6,
  16. Howard Stern8,
  17. Elizabeth Luis9,
  18. Hok Seon Kim3,
  19. Daniel Yansura3,
  20. Andrew S. Peterson1,
  21. Ellen Filvaroff4,
  22. Yan Wu3 and
  23. Junichiro Sonoda1,
  1. 1Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  2. 2Biomedical Imaging, Genentech Inc., South San Francisco, CA 94080, USA.
  3. 3Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
  4. 4Molecular Oncology, Genentech Inc., South San Francisco, CA 94080, USA.
  5. 5Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  6. 6Pharmacokinetic and Pharmacodynamic Sciences, Genentech Inc., South San Francisco, CA 94080, USA.
  7. 7Assay and Automation Technology, Genentech Inc., South San Francisco, CA 94080, USA.
  8. 8Pathology, Genentech Inc., South San Francisco, CA 94080, USA.
  9. 9Protein Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.
  1. To whom correspondence should be addressed. E-mail: junichis{at}gene.com

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