Research ArticleCancer

Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

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Science Translational Medicine  30 Nov 2011:
Vol. 3, Issue 111, pp. 111ra121
DOI: 10.1126/scitranslmed.3003161

Article Information

vol. 3 no. 111 111ra121

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 2, 2011
  • Accepted for publication November 4, 2011
  • .

Author Information

  1. Sameek Roychowdhury1,2,*,
  2. Matthew K. Iyer1,3,*,
  3. Dan R. Robinson1,4,*,
  4. Robert J. Lonigro1,3,
  5. Yi-Mi Wu1,4,
  6. Xuhong Cao1,4,5,
  7. Shanker Kalyana-Sundaram1,4,6,
  8. Lee Sam1,3,
  9. O. Alejandro Balbin1,3,
  10. Michael J. Quist1,4,
  11. Terrence Barrette1,4,
  12. Jessica Everett7,
  13. Javed Siddiqui1,4,
  14. Lakshmi P. Kunju1,4,
  15. Nora Navone8,
  16. John C. Araujo8,
  17. Patricia Troncoso8,
  18. Christopher J. Logothetis8,
  19. Jeffrey W. Innis9,
  20. David C. Smith2,10,
  21. Christopher D. Lao2,10,
  22. Scott Y. Kim11,
  23. J. Scott Roberts11,12,
  24. Stephen B. Gruber2,10,
  25. Kenneth J. Pienta1,2,10,13,
  26. Moshe Talpaz2,10 and
  27. Arul M. Chinnaiyan1,3,4,5,13,
  1. 1Michigan Center for Translational Pathology, Ann Arbor, MI 48109, USA.
  2. 2Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  3. 3Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.
  4. 4Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  5. 5Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  6. 6Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli 620024, India.
  7. 7Division of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  8. 8Division of Cancer Medicine, Department of Genitourinary Medical Oncology, M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  9. 9Department of Human Genetics and Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA.
  10. 10Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA.
  11. 11Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA.
  12. 12Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
  13. 13Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA.
  1. To whom correspondence should be addressed. E-mail: arul{at}umich.edu

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