Research ArticleAddiction

Molecular Mechanism for a Gateway Drug: Epigenetic Changes Initiated by Nicotine Prime Gene Expression by Cocaine

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Science Translational Medicine  02 Nov 2011:
Vol. 3, Issue 107, pp. 107ra109
DOI: 10.1126/scitranslmed.3003062

Article Information

vol. 3 no. 107 107ra109

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication August 15, 2011
  • Accepted for publication October 5, 2011
  • .

Author Information

  1. Amir Levine1,2,*,
  2. YanYou Huang1,2,
  3. Bettina Drisaldi1,
  4. Edmund A. Griffin Jr.2,3,
  5. Daniela D. Pollak2,,
  6. Shiqin Xu1,
  7. Deqi Yin1,
  8. Christine Schaffran2,
  9. Denise B. Kandel2,3,4, and
  10. Eric R. Kandel1,2,3,5,6,*,
  1. 1Department of Neuroscience, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA.
  2. 2New York State Psychiatric Institute, New York, NY 10032, USA.
  3. 3Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  4. 4Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
  5. 5Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  6. 6Kavli Institute for Brain Science, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  1. *To whom correspondence should be addressed. E-mail: ama146{at}columbia.edu (A.L.); erk5{at}columbia.edu (E.R.K.)

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