Research ArticleHutchinson-Gilford Progeria

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

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Science Translational Medicine  26 Oct 2011:
Vol. 3, Issue 106, pp. 106ra107
DOI: 10.1126/scitranslmed.3002847

Article Information

vol. 3 no. 106 106ra107

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication June 30, 2011
  • Accepted for publication September 20, 2011
  • .

Author Information

  1. Fernando G. Osorio1,
  2. Claire L. Navarro2,
  3. Juan Cadiñanos1,*,
  4. Isabel C. López-Mejía3,
  5. Pedro M. Quirós1,
  6. Catherine Bartoli2,
  7. José Rivera4,
  8. Jamal Tazi3,
  9. Gabriela Guzmán5,
  10. Ignacio Varela1,
  11. Danielle Depetris2,
  12. Félix de Carlos6,
  13. Juan Cobo6,
  14. Vicente Andrés4,
  15. Annachiara De Sandre-Giovannoli2,7,
  16. José M. P. Freije1,
  17. Nicolas Lévy2,7 and
  18. Carlos López-Otín1,
  1. 1Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.
  2. 2Université de la Méditerranée, Inserm UMR_S 910, Faculté de Médecine de Marseille, 13385 Marseille cedex 05, France.
  3. 3Institut de Génétique Moléculaire, UMR 5535 CNRS, 34293 Montpellier cedex 5, France.
  4. 4Departamento de Epidemiología, Aterotrombosis e Imagen, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain.
  5. 5Servicio de Cardiología, Hospital Universitario La Paz, 28046 Madrid, Spain.
  6. 6Departamento de Cirugía y Especialidades Médico-Quirúrgicas and Instituto Asturiano de Odontología, Universidad de Oviedo, 33006 Oviedo, Spain.
  7. 7AP-HM, Département de Génétique Médicale, Hôpital d’Enfants de la Timone, 13385 Marseille cedex 05, France.
  1. To whom correspondence should be addressed. E-mail: clo{at}uniovi.es

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