Research ArticleHuman Genetics

Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels

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Science Translational Medicine  15 Dec 2010:
Vol. 2, Issue 62, pp. 62ra92
DOI: 10.1126/scitranslmed.3001513

Article Information

vol. 2 no. 62 62ra92

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 21, 2010
  • Accepted for publication November 24, 2010
  • .

Author Information

  1. Julius Gudmundsson1,*,
  2. Soren Besenbacher1,*,
  3. Patrick Sulem1,*,
  4. Daniel F. Gudbjartsson1,
  5. Isleifur Olafsson2,
  6. Sturla Arinbjarnarson3,
  7. Bjarni A. Agnarsson2,4,
  8. Kristrun R. Benediktsdottir2,4,
  9. Helgi J. Isaksson2,
  10. Jelena P. Kostic1,
  11. Sigurjon A. Gudjonsson1,
  12. Simon N. Stacey1,
  13. Arnaldur Gylfason1,
  14. Asgeir Sigurdsson1,
  15. Hilma Holm1,
  16. Unnur S. Bjornsdottir4,
  17. Gudmundur I. Eyjolfsson5,
  18. Sebastian Navarrete6,
  19. Fernando Fuertes6,
  20. Maria D. Garcia-Prats7,
  21. Eduardo Polo8,
  22. Ionel A. Checherita9,
  23. Mariana Jinga9,
  24. Paula Badea10,
  25. Katja K. Aben11,12,
  26. Jack A. Schalken13,
  27. Inge M. van Oort13,
  28. Fred C. Sweep14,
  29. Brian T. Helfand15,
  30. Michael Davis16,
  31. Jenny L. Donovan16,
  32. Freddie C. Hamdy17,
  33. Kristleifur Kristjansson1,
  34. Jeffrey R. Gulcher1,
  35. Gisli Masson1,
  36. Augustine Kong1,
  37. William J. Catalona15,
  38. Jose I. Mayordomo18,
  39. Gudmundur Geirsson2,
  40. Gudmundur V. Einarsson2,
  41. Rosa B. Barkardottir2,4,
  42. Eirikur Jonsson2,
  43. Viorel Jinga9,
  44. Dana Mates10,
  45. Lambertus A. Kiemeney11,12,13,
  46. David E. Neal19,
  47. Unnur Thorsteinsdottir1,4,
  48. Thorunn Rafnar1 and
  49. Kari Stefansson1,4,
  1. 1deCODE genetics, IS-101 Reykjavik, Iceland.
  2. 2Landspitali-University Hospital, IS-101 Reykjavik, Iceland.
  3. 3Glaesibaer, Clinical Research Laboratory, IS-108 Reykjavik, Iceland.
  4. 4Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland.
  5. 5The Laboratory in Mjodd, IS-109 Reykjavik, Iceland.
  6. 6Division of Radiation Oncology, University Hospital, 50009 Zaragoza, Spain.
  7. 7Division of Pathology, San Jorge General Hospital, 22004 Huesca, Spain.
  8. 8Royo Villanova Hospital, 500014 Zaragoza, Spain.
  9. 9University of Medicine and Pharmacy Carol Davila, 020021 Bucharest, Romania.
  10. 10National Institute of Public Health, 050463 Bucharest, Romania.
  11. 11Comprehensive Cancer Center East, 6501 BG Nijmegen, Netherlands.
  12. 12Department of Epidemiology, Biostatistics and Health Technology Assessment, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, Netherlands.
  13. 13Department of Urology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, Netherlands.
  14. 14Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, Netherlands.
  15. 15Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  16. 16School of Social and Community Medicine, University of Bristol, Bristol BS8 1TH, UK.
  17. 17Nuffield Department of Surgical Science, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
  18. 18Division of Medical Oncology, University Hospital, 50009 Zaragoza, Spain.
  19. 19Oncology Centre, Addenbrooke’s Hospital, University of Cambridge, Cambridge CB2 0QQ, UK.
  1. To whom correspondence should be addressed. E-mail: kstefans{at}decode.is (K.S.); julius{at}decode.is (J.G.)

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