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Abstract
A report in this issue of Science Translational Medicine reveals that amplification of the FGFR1 gene—which encodes fibroblast growth factor receptor 1—is a major oncogenic aberration in squamous cell lung cancer. This genetic variation may represent the first relatively high-frequency therapeutic target of smoking-associated lung cancer.
Footnotes
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Citation: N. C. Turner, M. J. Seckl, A therapeutic target for smoking-associated lung cancer. Sci. Transl. Med. 2, 62ps56 (2010).
- Copyright © 2010, American Association for the Advancement of Science