Research ArticlePrenatal Diagnosis

Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus

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Science Translational Medicine  08 Dec 2010:
Vol. 2, Issue 61, pp. 61ra91
DOI: 10.1126/scitranslmed.3001720

Article Information

vol. 2 no. 61 61ra91

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 17, 2010
  • Accepted for publication November 18, 2010
  • .

Author Information

  1. Y. M. Dennis Lo1,2,*,
  2. K. C. Allen Chan1,2,
  3. Hao Sun1,2,
  4. Eric Z. Chen1,2,
  5. Peiyong Jiang1,2,
  6. Fiona M. F. Lun1,2,
  7. Yama W. Zheng1,2,
  8. Tak Y. Leung3,
  9. Tze K. Lau3,
  10. Charles R. Cantor4 and
  11. Rossa W. K. Chiu1,2
  1. 1Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
  2. 2Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
  3. 3Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
  4. 4Sequenom Inc., San Diego, CA 92121–1331, USA.
  1. *To whom correspondence should be addressed. E-mail: loym{at}cuhk.edu.hk

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