Contents
Vol 2, Issue 57
Contents
Commentary
- Achieving a Nationwide Learning Health System
An infrastructure that enables secure reuse of patient data can speed the progression of new knowledge from bench to bedside.
Research Articles
- TLR9 Differentiates Rapidly from Slowly Progressing Forms of Idiopathic Pulmonary Fibrosis
Compared to slow progressors, patients with rapidly progressive idiopathic pulmonary fibrosis express more TLR9, which recognizes unmethylated CpG DNA and stimulates the fibrotic process.
- Prevention of Muscle Aging by Myofiber-Associated Satellite Cell Transplantation
Transplantation of myofibers and associated stem cells into injured muscle protects against age-related muscle degeneration in mice.
Editors' Choice
- Breathe Bitter, Breathe Easy!
Bitter taste receptors in lungs might help relax asthmatic airways.
- New Cellular Culprits in Gaucher's Disease
Gaucher's disease is caused by defects in osteoblasts, dendritic cells, and T cells, as well as macrophages.
- The Virus in the Machine
HIV interferes with dopamine function in the brain's subcortical motor system, explaining some of its neurological effects.
- Attacking Lung Cancer, One Mutation at a Time
Lung cancers that carry the EML4-ALK translocation are uniquely sensitive to an ALK inhibitor.