Contents
Vol 2, Issue 56
Contents
Research Articles
- Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2
Children who carry one variant of a brain protein associated with autism exhibit fewer long-range connections between the prefrontal cortex and more posterior brain regions.
- Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease
Oxysterols are biomarkers for diagnosis and drug treatment in Niemann-Pick C1 disease.
Review
- Mathematical Modeling of Molecular Data in Translational Medicine: Theoretical Considerations
Appropriate data modeling strategies must be used when analyses generate tens of thousands of data points from individual study participants.
Editors' Choice
- Metabolic Syndrome: Pass It On!
Overnutrition in neonatal males may yield epigenetic changes that specify adverse metabolic phenotypes in subsequent generations.
- Stopping the Drilling and the Filling: Regenerating Teeth with Soluble Human Tooth Proteins
New research into human tooth proteins may lead to ways to regenerate tooth structures and treat tooth decay.
- Exomes Take Center Stage
Sequencing exomes identifies a new gene variant causing familial combined hypolipidemia.
- The New Dish on Fish
In spite of its beneficial reputation, fish oil may promote colon cancer in mice with chronic colitis by decreasing immune function.