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p11 and Gene Therapy for Severe Psychiatric Disorders: A Practical Goal?

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Science Translational Medicine  20 Oct 2010:
Vol. 2, Issue 54, pp. 54ps51
DOI: 10.1126/scitranslmed.3001754

Article Information

vol. 2 no. 54 54ps51

DOI: 
https://doi.org/10.1126/scitranslmed.3001754
PubMed: 
20962329
Published By: 
American Association for the Advancement of Science
Print ISSN: 
1946-6234
Online ISSN: 
1946-6242
History: 
  • .
Copyright & Usage: 
Copyright © 2010, American Association for the Advancement of Science

Author Information

  1. Guang Chen1,
  2. Roy Twyman2 and
  3. Husseini K. Manji2,*
  1. 1Neuroscience, Johnson & Johnson Pharmaceutical Research and Development, La Jolla, CA 92121, USA.
  2. 2Neuroscience, Johnson & Johnson Pharmaceutical Research and Development, Titusville, NJ 08560, USA.
  1. *Corresponding author. E-mail: hmanji{at}its.jnj.com

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  • p11 and Gene Therapy for Severe Psychiatric Disorders: A Practical Goal?

    By Guang Chen, Roy Twyman, Husseini K. Manji

    Science Translational Medicine : 54ps51

    Levels of the p11 protein in the nucleus accumbens brain region are lower in individuals with depression, and p11 appears to modulate depression-related behaviors in mice.

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