Contents
Vol 2, Issue 52
Contents
Commentaries
- Opening Up to Precompetitive Collaboration
The move to increase biomedical R&D efficiency and innovation has stimulated the development of collaborations, among competitors, that span the precompetitive space.
- The Bayh-Dole Act Turns 30
The act that gave U.S. institutions the right to claim title to inventions resulting from federally funded work dramatically increased public benefits from research.
Research Articles
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
A human antibody to interleukin-17A is well tolerated and may be effective in the treatment of psoriasis, rheumatoid arthritis, and noninfectious uveitis.
- PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
Abnormal expression of genes for energy regulation in Parkinson’s disease patients identifies a master regulator as a possible therapeutic target for early intervention.
Editors' Choice
- Turning Off the Cancer Switch
A new drug that blocks BMK1 inhibits tumor growth with minimal toxicity.
- PANDERing to the Liver in Glucose Control
A new cytokine-like protein produced by the pancreas regulates glucose production in the liver during fasting.
- Making Comparative Effectiveness Research Useful
The value of comparative effectiveness research depends on applying appropriate design and analysis principles.
- Bridging the Gap in Spinal Cord Injury
Valproic acid coaxes transplanted neural stem cells to differentiate into neurons that boost repair of spinal cord injury in mice.